Sunday, October 27, 2019

Prostate Cancer News- Important Therapeutic study on Radiation combined with Hormone Antagonist



Carrie C, Magné N, Burban-Provost P, et al. Short-term androgen deprivation therapy combined with radiotherapy as salvage treatment after radical prostatectomy for prostate cancer (GETUG-AFU 16): a 112-mont follow-up of a phase 3, randomised trial [published online October 16, 2019]. Lancet Oncol.  doi: 10.1016/S1470-2045(19)30486-3.

The GETUG-AFU 16 trial enrolled patients from October 19, 2006 to March 30, 2010. Dr Carry and his collaborators randomly assigned 743 men with to receive radiotherapy alone (374 patients) or radiotherapy in addition to goserelin (369 patients). One patient in the radiotherapy alone group later withdrew consent, leaving 373 patients in that group. The median follow-up was 112 months. In the first analysis of the trial, which was published in 2016, only the first progression event was collected, so MFS could not be analyzed, the authors noted.


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