Prostate Cancer News- Important Therapeutic study on Radiation combined with Hormone Antagonist

Carrie C, Magné N, Burban-Provost P, et al. Short-term androgen deprivation therapy combined with radiotherapy as salvage treatment after radical prostatectomy for prostate cancer (GETUG-AFU 16): a 112-mont follow-up of a phase 3, randomised trial [published online October 16, 2019]. Lancet Oncol.  doi: 10.1016/S1470-2045(19)30486-3.

The GETUG-AFU 16 trial enrolled patients from October 19, 2006 to March 30, 2010. Dr Carry and his collaborators randomly assigned 743 men with to receive radiotherapy alone (374 patients) or radiotherapy in addition to goserelin (369 patients). One patient in the radiotherapy alone group later withdrew consent, leaving 373 patients in that group. The median follow-up was 112 months. In the first analysis of the trial, which was published in 2016, only the first progression event was collected, so MFS could not be analyzed, the authors noted.

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Bowery Creative Propels PaceyCuff

Bowery Creative Propels PaceyCuff

It is with great expectations that we engage the power of Bowery Creative 

to continue our drive to commercialization .

Pacey Medtech has been diligently working to expand the quality and 

range of capability of the PaceyCuff System and develop the distribution

network at the same time.

Welcome  Guy, Sarah, and the Bowery Team.

                Go to PaceyCuff for information .   paceycuff.com

PaceyCuff introduces the "POWER SLEEVE"

                                                    PaceyCuff System

                               PaceyCuff introduces the "POWER SLEEVE"

The rollout of the "PaceyCuff POWER SLEEVE" is beginning with distribution to users who have had difficulty with pinching issues or sizing issues.
The concept is that the POWER SLEEVE is that collecting and controlling of penile skin provides resolution of the skin pinching issue and also allows diminished variability for application of the cuff.
The net result of reduced pinching and improved continence is very beneficial for users and greatly enhances the PaceyCuff System.

This development will greatly benefit the Pacey Medtech Ltd. company and will allow us to commercialize our other innovations to benefit patients.

PaceyCuff Association with Peapod Mats

Pacey Medtech meets with Peapod Mats 

Outstanding Vancouver company and veterans of Dragon's Den Canada meets with Pacey Medteech to share great war stories and not a few moments of humour.  Peapod Mats great online  service and great contribution to the field of continence is well known in North America and elsewhere. There is a natural interest in learning and sharing ways of helping people with incontinence. The Peapod Mat is super technology as is the PaceyCuff.

Brachytherapy urinary incontinence and PaceyCuff

Send to

Brachytherapy induced uroincontinence is a well known but infrequent (4.4%) result of therapy.
Whereas the post surgical result , often including radiation Rx may be 11-12% .
PaceyCuff urethral control device may be used in both forms of the complication.
paceycuff.com

Urology. 2016 Sep;95:151-7. doi: 10.1016/j.urology.2016.05.021. Epub 2016 May 19.

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Urinary Incontinence Following Prostate Brachytherapy.

Leapman MS1, Stone NN2, Mock S3, Stock RG2, Hall SJ4.

OBJECTIVE:

To define the incidence, time course, and risk factors associated with the
development of urinary incontinence (UI) following prostate brachytherapy.

MATERIALS AND METHODS:

A total of 2461 men were identified who underwent permanent
 interstitial prostate brachytherapy with or without external
beam radiation therapy. We examined the relationship between clinical- and treatment-related
 variables with the onset of UI, defined as leakage requiring pad usage, and further classified
 as stress (SUI) or urge (UUI) predominant, using univariate and Cox proportional hazards
regression models. The changes in International Prostate Symptom Score and quality of life
domains were assessed from baseline to last follow, and examined by UI status.

RESULTS:

Patients were followed for a median of 6.4 years (interquartile range 4.1-9.3).
UI was reported in 108 individuals (4.4%), at a median of 1.8 years
(interquartile range 5 months-4.4 years): 30 with SUI and 78 with UUI. Seventy-two men (66.7%)
 reported using 1, 24 (22.2%) using 2, and 12 (11%) using ≥3 pads per day. On multivariate
analysis, post-implantation transurethral resection of the prostate, urinary retention, 
external beam radiation therapy, and higher pretreatment International Prostate 
Symptom Score were significantly associated with the development of SUI, 
although transurethral resection of the prostate was the only significant risk factor 
associated with SUI. Men experiencing UI reported greater declines in urinary 
quality of life; however, no significant difference was observed between SUI and UUI.

CONCLUSION:

UI occurred in 4.4% of patients following prostate brachytherapy
and is more commonly urge-predominant in character. Distinct risk factors
exist for the development of UUI vs SUI. Urinary leakage requiring pad usage was associated
with declines in urinary QOL.

News Coming On the PaceyCuff Guard

Pacey Cuff Guard News

Please stand by for more good news on the PaceyCuff Guard device. 

Pacey Medtech is finding an eager market for the reusable Guard concept and while the PaceyCuff continues to benefit from ongoing research the Guard is also getting more robust and useful. News will be published soon on this topic.

The goal of Pacey Medtech is to provide a suite of products for male and female incontinence that will provide choices that accommodate personal variance . The evolution of the products will therefore make them more and more effective.

PaceyCuff Guard and PaceyCuff

PaceyCuff usage Strategy

Patients with Bladder incontinence will understand that we are dealing with a very difficult problem.

Tools that are available are limited so we have created the PaceyCuff System that includes the PaceyCuff and the PaceyCuff guard.

PaceyCuff continues to evolve and upgrade performance due to customer feedback and also ongoing engineering input.

1. Overall strategy- because we are preserving the circulation with our device the traditional clamp practice of complete over pressuring of the Penis is not permitted. The PaceyCuff has a goal to offer great control that is backed up by a pad or ideally the PaceyCuff Guard. This is a combined strategy to cope with this very challenging problem.

2. When the bladder is empty or 1/2 full the pressures are modest and little leakage will be experienced however as filling progresses the stress or pressure incontinence begins to appear. Therefore frequent voiding, when the urge presents itself , assists with keeping dry. 

3. Moderate fluid intake is also a benefit as it keeps the volume in the bladder low.

4. The PaceyCuff Guard gives users good opportunities for an environmentally sound PaceyCuff backup device. The guard has enough adsorbancy to retain drips but if leakage is more of an issue some added absorbant materiel may be added. 

Many PaceyCuff users opt for the PaceyCuff Guard when they purchase and then learn to use the devices together. 

PaceyCuff Guard Features

Pacey Cuff Guard

     The Guard device is designed to function during the day as well as at night to capture small leaks and provide extra protection to users. If the Guard and Cuff are considered to be parts of a system that is mutually supportive then one would expect that one or more Guards would be useful for each Cuff.

The function of the Guard is enabled by the inner surface which has an adsorptive layer of velour adjacent to the skin. The patent pending Adsorptive* capability is enabled by the monofilament loop field which attracts water or urine by molecular forces alone. These forces can lock down a moderate amount of urine but also release it easily by a simple water rinse or soap and water wash. Drying is best done by compression of the damp device between two layers of towel followed by air dry. The use of a hair dryer on a warm cycle can complete the process in minutes if a rapid turnaround is necessary. 

This device will dramatically reduce the number of pads that end up in the landfill and therefore represents a "Green" solution. Rugged construction assures a long service life. 70% methanol spray or alcohol based aftershave  may be used from time to time to be certain that no bacterial contamination will develop.

*Adsorption:  relies on the molecular attraction of water to the loops of monofilament on a closed cell foam base material.

Absorption:  relies on a material that has open cell structure that allows water to enter into the structure. This is much harder to clean and dry so we do not use these kinds of materials.

Bladder Strategy- How does the condition of the Bladder affect the application of the PaceyCuff to Post Prostatectomy Incontinence.

The Bladder and PaceyCuff use.

        The PaceyCuff Urethral Control Device has proven to be a versatile solution for use by patients with post prostatectomy incontinence. The device has a learning path for users which over time makes the control and comfort better. Pacey Medtech is developing products that improve the control and comfort of the device such as the PaceyCuff Guard product now on Sale via Amazon and Pacey MedTech web sales channel. Other offerings are imminent so stand by for these exciting developments.

       Pacey MedTech plans to develop the finest suite of products available for this space such that we become the Best in Class source of products.

      

       The PaceyCuff depends on the underlying condition of the bladder for most effective use. PMT teaches that users should completely empty the bladder from the most effective standing position wherein the abdominal pressure presses down on the bladder to assist emptying. 

A problem can exist when the bladder outlet scarring , post surgery or radiation,  prevents the complete emptying of the bladder. This can cause retention of a substantial quantity of urine which is easily pushed out of the bladder by coughing , straining, or physical activity like skiing.

      The  urologist can confirm this by cystoscopy but there is a simpler solution for the issue wherein one can do a self catheterization with a 12-14 F size catheter if this is recommended by medical advisors of the patient. The catheterization should be done when the bladder is considered to be empty. If residual urine is present at this time one will know that bladder emptying is incomplete. The process of catheterization also tends to solve the problem by dilating the bladder outlet.

       Be sure to contact your medical advisor prior to any attempt at self catheterization.

Pacey Medtech announces Distribution in Germany and Switzerland - Medical Technology Marketing

   

                                                       MTM 

Pacey Medtech is very Pleased to announce the engagement of mtm | medical technology marketing e.K. as a distribution partner selling in Germany and Switzerland.

Mathias Werner outstanding company has developed a large presence in the field of Continence management and  has a substantial number of patients under care.

The excellent presentation of PMT PaeyCuff can be seen on the following link!

http://www.mtm-med.com/produkte-pacey_cuff

Contact:

mtm | medical technology marketing e.K.

           Waffenschmiedweg 30 a | 86911 Diessen | Germany

            Tel.: +49 (0) 9907-91138 | Fax: +49 (0) 8807-940899

    E-Mail: mw@mtm-med.com | Internet: www.mtm-med.com

Handeslregister | Registration: Amtsgericht Augsburg, HRA 18206