paceycuff.com
Q. What do Your Doctors Recommend when you have Had Radiation or Surgery and your PSA continues to rapidly Rise in Spite of AntiAndrogen Therapy?
A. Not so much .
Exciting new research has changed all of this!
Now a new Treatment path has been shown to provide 20 or more months of metastasis free survival time than previous watchful waiting.
Remember this is a specific group of patients but it is not a small group that can now be substantially helped. ( currently 100,000 in the USA).
Spartan Trial 1207 patients (Janssen Biotech)
Oral androgen receptor inhibitor-Apalutamide.
The metastasis free survival was 40 months compared to 26 months for the control group treated with antiandrogen therapy alone.
Prosper Trial (Pfizer group)
Earlier oral androgen receptor inhibitor-Enzalutamide.
The metastasis free survival was 36.6 months compared to 14.7 months for the control group treated with antiandrogen therapy alone.
The 2 trials will be reported this week at the Genitourinary Cancer Symposium 2018 in San Francisco where it is expected these drugs will propel a major change in therapy.
Both trials were done on men post treatment who had PSA double within 10 months time span indicating active cancer cell development.
The unanswered question of which drug is superior must remain conjecture until a proper head to head comparison is carried out.
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